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Similarly, colitis disrupts the intestinal barrier and results in gastrointestinal inflammation, which increases BBB permeability and neuroinflammation [238, 239]

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The tirzepatide before and after data shows similar threshold effects at the 15% mark, reinforcing that this is a physiologically meaningful breakpoint across compound classes

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Drinking small sips of clear liquids periodically can help if youre feeling nauseous or keep throwing up